[WorldNetDaily: Worldwide prayer urged on 03-03-03] It cannot hurt to do prayer at this time as they are asking (at 3:33 PM, though 3:33 AM would be a greater sacrfice for most). But I always thought the Bible said that we were to 'pray without ceasing'.

1 Thessalonians 5:16-22 16 Rejoice evermore. 17 Pray without ceasing. 18 In every thing give thanks: for this is the will of God in Christ Jesus concerning you. 19 Quench not the Spirit. 20 Despise not prophesyings. 21 Prove all things; hold fast that which is good. 22 Abstain from all appearance of evil.